Sematide 0.25MG PES Injection

SEMATIDE 0.25MG PFS INJ
Support your diabetes management with SEMATIDE 0.25MG PFS INJ, a prefilled semaglutide injection designed to help improve blood sugar control in adults with type 2 diabetes when used alongside diet and exercise. Its once-weekly dosing offers convenience while supporting long-term glycemic management.

Requires Prescription
Yes

Generics
Semaglutide

Used For
Type 2 Diabetes Mellitus

How it Works
Semaglutide is a GLP-1 receptor agonist that mimics the action of the natural GLP-1 hormone. It helps lower blood sugar by stimulating insulin release when glucose levels are high, reducing glucagon secretion, and slowing gastric emptying, which may also help support appetite control. Its prolonged action allows for convenient once-weekly dosing.

Usage and Safety

Dosage
Treatment is usually started with 0.25 mg once weekly for 4 weeks. This starting dose is intended for treatment initiation and is not for glycemic control. After 4 weeks, the dose is typically increased to 0.5 mg once weekly, with further adjustments made by your physician if needed. Use exactly as directed by your healthcare provider.

Side Effects
Common side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Changes related to diabetic eye disease (retinopathy)

Less common but serious side effects may include:

• Pancreatitis
• Severe allergic reactions
• Vision changes

Seek medical attention if severe or unusual symptoms occur.

Drug Interactions
Use with insulin or sulfonylureas may increase the risk of low blood sugar (hypoglycemia). Your doctor may adjust other diabetes medications if needed.

Indication
Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.

When Not to Use

Do not use if you have:

• Personal or family history of medullary thyroid carcinoma (MTC)
• Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
• Allergy to semaglutide or any component of the product

Precautions

Use with caution in patients with:

• Diabetic retinopathy
• History of pancreatitis
• Kidney impairment
  Regular monitoring may be required during treatment.

Warnings

Warning 1
Not for use in type 1 diabetes or diabetic ketoacidosis. This medicine is not a substitute for insulin.

Warning 2
Gastrointestinal side effects such as nausea, vomiting, or diarrhea may lead to dehydration and may affect kidney function.

Warning 3
Stop use and seek medical advice if symptoms of pancreatitis occur, such as severe persistent abdominal pain.

Additional Information

Pregnancy Category
Always consult your physician before using any medicine during pregnancy or breastfeeding.

Storage
Store in a refrigerator at 2°C to 8°C.
Do not freeze. Keep out of reach of children.