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In adults with type 2 diabetes mellitus, empagliflozin is recommended as a supplement to diet and exercise to improve glycemic control as:When a patient's diet and exercise are insufficient to achieve adequate glycemic control and the use of metformin is deemed inappropriate due to intolerance, the patient may benefit from monotherapy.Supplementary combination therapy: when diet, exercise, and other glucose-lowering medications are insufficient to achieve appropriate glycemic control, in conjunction with insulin and other medications.
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